Sentence examples for mutation spectrum data from inspiring English sources

Our desire to extract biologically meaningful mutational signatures, as well as the intrinsic nonnegativity of the mutation spectrum data, renders NMF an appropriate choice for factorizing the data from the 21 cases.

For calculating statistical differences in the mutation spectrum data the chi-squared test was used.

Evaluation of TP53 mutations as biomarkers of mutagenic events is an advantageous scientific utilization of TP53 mutational spectrum data.

Because the polymorphism timescale encompasses less time for this assumption to be violated, the cSNP data should be closer to the true mutation spectrum than the cSNS data.

Provide the end user with an interface for easy data query and retrieval of information pertaining to the mutation spectrum of each disorder together with the corresponding mutation frequencies and references.

Over the past 15 years only a minority of the published studies which have attempted to correlate mutational and IQ data have reported mutations across the full mutation spectrum seen in the DMD gene [1], [26], [32] [36].

Extended Data Fig. 8 Distribution of somatic mutation spectrum in NF1-glioma.

We also managed to rapidly identify the mutation spectrum occurring in the mutant genomes using the output data.

This would yield too few data for a full analysis of recombination and mutation spectrum at centromeres.

Continuous efforts will be made to (i) collect the latest mutation data related to IRD, (ii) perform extended functional analysis based on the updated data sets and (iii) improve the gene disease network, mutation spectrum and other database functionalities.

We used RNA-Seq data from tumor and matched normal samples to investigate somatic mutation spectrum in OSCC.