Sentence examples for mutation spectrum and from inspiring English sources

We applied our pipeline to determine the degree of clonal expansions and make adjustments to determine mutation frequency within our population of mutants for each mouse, to precisely characterize spontaneous and BaP-induced mutation spectrum, and to determine the mutational hotspots across the lacZ locus in both control and BaP-exposed mice.

We performed mutation spectrum and signature analysis to explore the relationship within tumor samples in each same patient.

Blanchon, S. et al. Delineation of CCDC39/CCDC40 mutation spectrum and associated phenotypes in primary ciliary dyskinesia.

Stensland, E. et al. Prevalence, mutation spectrum and phenotypic variability in Norwegian patients with limb girdle muscular dystrophy 2I.

We aimed to revisit PKD2 prevalence, clinical presentation, mutation spectrum, and prognosis through the Genkyst cohort.

The NOEY2 gene mutations and protein expression in human breast cancers, adjacent breast tissues and breast benign lesions were analysed to explore the potential correlation between the mutation spectrum and breast cancer development and progression.

Sequencing of the UV-induced lacZ′ mutants provided mutation spectra and mutational hot spots for the various UV regions.

This study provides important insights into the extent of mutational variation among related animal lineages, and the interrelationships between underlying mutation spectra and patterns of natural polymorphism at loci widely presumed to be neutral.

To investigate mutation spectrums and their correlations to phenotypes in Noonan syndrome (NS) and NS-related disorders that share functional alterations of the Ras-mitogen-activated protein kinase pathway.

Traditionally, analyses of mutation spectra and rates have been based on a small portion of phenotypically and molecularly detectable loci.

Other studies have identified gene mutation spectra and gene expression profiles associated with biological processes that are altered in lung cancer [ 3, 34], resulting in improved sensitivity.