Sentence examples for mutation spectra in from inspiring English sources

Analysis of mutation spectra in yeast also showed that MMR mutants (msh2, msh6, mlh1 and pms1) had increased frameshift mutation rates in non-repetitive regions compared to wild-type [53].

It should be noted that MMR failure also promotes mutations in non-repetitive regions of DNA (in addition to microsatellite sequences), as shown by studies on mutation spectra in human cells [49] [52].

The p16, BRCA1 and the BRCA2 mutation data were from the databases of mutation spectra in the p16 gene [ 28] and the BRCA1 and BRCA2 genes [ 29].

Furthermore, analysis of the 94 substitutions on mutation bias revealed very similar mutation spectrum to the spontaneous mutation spectra in N2 (C.

7 8 Existing data from different FAP patients support the existence of different APC mutation spectra in tumours from different locations in the bowel.

Here we developed a high-throughput and cost-effective approach that uses NGS to characterize lacZ mutation spectra in the Muta™Mouse model.

Analysis of the p53 exon 5 mutation spectrum in mutation databases for lung cancer reveals frequent GC > AT transitions, several of which occur at non-CpG sequences.

To study the clinical variability and KCNV2 mutation spectrum in cone dystrophy with supernormal rod response (CDSRR) in the Israeli population.

The objective of this study was to update and reveal the prevalence of thalassemia and mutation spectrum in the Baise region of southern China.

In general, the strand-biased mutation spectrum in animal mitogenomes results in an AC-rich L strand and a GT-rich H strand.

This is in line with Kastritis et al. [12], who also noted an underrepresentation of truncating mutations compared to the mutation spectrum in colorectal cancer.