Sentence examples for mutation spectra determined from inspiring English sources

The mutation spectra determined using the NGS analytical process are highly concordant with results using Sanger sequencing, demonstrating the accuracy of the methodology.

For many ethnic or geographic populations, the mutation spectrum has been determined [ 6– 15].

We applied our pipeline to determine the degree of clonal expansions and make adjustments to determine mutation frequency within our population of mutants for each mouse, to precisely characterize spontaneous and BaP-induced mutation spectrum, and to determine the mutational hotspots across the lacZ locus in both control and BaP-exposed mice.

In contrast, only independent mutations were used to determine the lacZ mutation spectra for both groups.

Sequencing of the UV-induced lacZ′ mutants provided mutation spectra and mutational hot spots for the various UV regions.

The mutation spectra of three cell lines (parental T54c10 and two +MBD4tru clones T57c12 and T57c32) were determined by sequencing about 50 independent mutations.

To determine whether strand specific mutation biases are a general characteristic of geminivirus evolution we compared mutation spectra arising during these MSV experiments with those arising during similar experiments involving the geminivirus Tomato yellow leaf curl virus (Begomovirus genus).

The mutation spectra differed in each case.

Human intestinal tumour mutation spectra were analysed.

Bone marrow mutation spectra of control and BaP treatments.

Comparison of BaP-induced and spontaneous mutation spectra.