Sentence examples for mutation so the from inspiring English sources

"At a certain point, there's a fitness cost for adopting a new mutation, so the virus says, 'What else can I do?' " says Nabel.

However, the 65 bp deletion in the second exon of the distal copy of CG32712 causes a nonsense mutation, so the associated mRNA cannot produce functional proteins.

In the absence of ZNF304, these tumor suppressor genes remained switched on in cancer cells with the KRAS mutation, so the growth of the tumor was slowed down.

Although the study observed no association between HFE C282Y genotype, transferrin saturation and very low birth weight, it should be noted that only six infants were heterozygous for the HFE C282Y mutation so the study was very underpowered to test this hypothesis.

Of the 14 RCML patients, only one BC patients carried ABL kinase domain mutations, so the different metabolic phenotypes of RCML and SCML are not necessarily dependent on ABL domain mutations.

TFs have evolved by accumulating mutations, so the complexity in gene regulation patterns has increased.

Rather, ChemGenex had not specified a companion test that could reliably detect the mutation so that the drug could be given to the patients it is intended to help.

The strain was out-crossed to remove the facA700 mutation so that the acetate repression phenotype could be more directly monitored in the absence of the glycerol needed to provide a carbon source in a facA700 strain.

However, a click of Muller's ratchet eventually results in the fixation of a mutation, so that the number of fixed mutations (mfix) far exceeds the number of segregating mutations in the least-loaded class (mLLC − mfix).

Thus the more frequently a given gene contains a silent mutation, the more frequently such mutations should co-occur with a KRAS mutation, so that the number of co-mutations should increase in a linear fashion as described above.

In this hereditary cancer syndrome, tumors form following a second (somatic) mutation, so that the function of both alleles of VHL in these cells has been disrupted (21– 21).