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We studied 25 HIV newly diagnosed patients with the E138A mutation since the year 2010.
In hereditary antithrombin (AT) deficiency it is important to determine the underlying mutation since the future risk of thromboembolism varies considerably between mutations.
The EPD has alarmed Stephany's new GP with a pop-up that Stephany is carrier of a BRCA2 mutation since the clinical geneticist not only diagnosed Angela with a mutation, but unfortunately also her two daughters.
In both instances, the authors were aware that this pastoral economic system had undergone a mutation since the demise of the Sultanate, and thus, the dichotomous or holistic characterization amounted to an expedient reductionism: the first to validate a theory, and the second to justify a policy.
For B6, the workflow produced, as expected, only 1 SAP entry, a likely false positive or recent mutation since the mouse reference genome is based on B6 [ 26].
These examples may also provide candidates to be re-examined for evidence of frameshift mutation since the failure to recognize a frameshift mutation would result in a nucleotide alignment with the signature of successive non-synonymous substitutions.
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This is obviously a consequence of the mutation, since this position of the PLP ring is also observed in the unliganded forms of T254A and T254C rcSHMT structures.
Another predicament with the TnT approach pertains to unexpected presence of the fourth type of nucleotide in the repeat region, most frequently due to a mutation, since this prevents the creation of a complete thread.
It might be considered likely that crd in MLDH and SWDH was caused by the same mutation, since these two breeds have in part the same genetic background.
It would be tempting to conclude that the sensitivity to p110α inhibitors is a direct consequence of the presence of the H1047R mutation, since this isoform has increased catalytic activity [ 13].
We excluded from the analyses mice that were homozygous for the Pde6d mutation since these mice develop blindness overtime [16], representing a confounding factor in neurobehavioural analyses, and in particular for spatial learning tasks.
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