Sentence examples for mutation showing a from inspiring English sources

ALK, PHOX2B and PHOX2A silencing was achieved through gene-directed siRNA in three NB cell lines, namely IMR-32, HTLA-230 and SH-SY5Y, this latter carrying a p.F1174L ALK mutation, showing a high expression of the three genes.

In this study, pseudogenes were separated in two groups, with the group of pseudogenes with one mutation (showing a low mutation rate) and the second group with an elevated mutation rate (>4 mutations, on average).

Binding of PpIX to RsTSPO was also influenced by the W38C mutation, showing a 6-fold decrease in affinity (from 2 to 0.3 μM), consistent with both binding sites involving W38C in the conserved region of loop 1.

All 13 cases of colorectal carcinoma with a KRAS mutation showed a gross polypoid configuration, compared to no KRAS mutation in the colorectal carcinomas with ulcerative configuration.

Fibroblast cells derived from DOA patients with missense mutation showed a significant impairment of oxidative phosphorylation (OXPHOS), mostly mediated by complex I [27].

The proband, who carried the mutation, shows a more severe phenotype than his brother and exhibited sleep disorder during early childhood whereas his brother did not.

Patients with a T790M mutation showed a more favorable prognosis.

Individuals with a T=>G mutation show a substantially increased risk for developing colorectal cancer.

Splice site predictions for the c.436C>T mutation showed a new PLP1 splice donor site at c.434.

The patient carrying the P69L mutation shows a relatively late age at onset of endocrine disease.

However, in several stratifications, KRAS mutation showed a trend towards significance (P ≤ 0.05).