Sentence examples for mutation selected in from inspiring English sources

In our analysis, daily dosing of NVP did not alter the dominant NVP-resistant mutation selected in infants infected in the first six of weeks of life.

A mutation selected in 1 gene can potentially lead to an amino acid change in the overlapping reading frame.

Mutations in EF-G may also indicate fine tuning of adaptation to narrow windows of antibiotic concentration: a mutation selected in a low sublethal concentration of the antibiotic resists a higher concentration poorly, though one selected in the latter performs better at this concentration despite the two mutations targeting the same amino acid residue (P to T versus P to L).

We did not observe any of the most common amino acid substitutions in K13 associated with artemisinin resistance in P. falciparum isolates from Cambodia (C580Y, R539T or Y493H) (3 ), nor the I543T and N458Y mutations most strongly associated with increased clearance t1/2 in another recent study (4 ), nor the M476I mutation selected in vitro under artemisinin pressure (3 ).

Results: Three new mutations, selected in the presence of PFA, were identified with single base substitutions resulting in T419M, Q578H, and L773V in conserved regions of the HCMV DNA polymerase.

Pattern of mutations selected in the NVP group (Y181C/V, K101E) showed a predicted decreased susceptibility to etravirine or rilpivirine in 50% of individuals.

Second, we ask whether and how pleiotropic effects of mutations selected in the presence of both CTX and CAZ affect adaptation to these antibiotics.

This finding suggests that mutations selected in the spontaneously resistant B. cenocepacia J2315 mutants are stably inherited and do not revert at a high frequency.

Interestingly, specialization largely halts after the first round, and mutations selected in later rounds are approximately equally beneficial for CTX and CAZ resistance (Figs 2A and 4).

Nevertheless, reversion S164R remains beneficial in all tested genetic backgrounds when switching from CAZ back to CTX in round 3, suggesting additional ameliorating effects from other mutations selected in these lines.

Moreover, obviously this was not due to mutations selected in the evolutionary engineering optimization of Isoy17 from Isoy16, as in other isobutanol fermentations Isoy16 and 17 transformants performed nearly the same (see below).