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The somatic mutation score reported by ClinSeK is the Phred-scaled P(M rv | D).
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Injury score reported?
Median/mean injury score reported.
How are the scores reported?
All LOD scores reported are multipoint.
Homozygous mutants were determined by comparing the ratio of two overlapping peaks with that of neighboring SNPs (intrinsic SNPs among three loci) and a mutation score greater than seven as reported by Mutation Surveyor®.
We verified the reported SNPs with Mutation surveyor program version 2.51 by visual inspection, sequence quality (>10) and mutation score (>20) which correspond to a confidence of 99% for correct call.
The main outcome of the mutation analysis is the mutation score, which indicates the effectiveness of a test suite.
It is possible to realize that the column "Mutation Score" contains the mean of the mutation scores obtained by each test set (RP_1), (RR_1), (RP_2) and (RR_2), respectively.
Clearly the mutation score obtained by the combined test sets is always greater than the score obtained by individual sets.
Considering the mean of 30 (RP_1) sets, a mutation score of 90.7 % was obtained.
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CEO of Professional Science Editing for Scientists @ prosciediting.com