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Clearly the mutation score obtained by the combined test sets is always greater than the score obtained by individual sets.
Figure 9 presents a bar chart with the mutation score obtained by the tests generated by BETA with each input space partitioning criterion and logical coverage criterion in each experiment.
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It is possible to realize that the column "Mutation Score" contains the mean of the mutation scores obtained by each test set (RP_1), (RR_1), (RP_2) and (RR_2), respectively.
Thus, in each Table 2, 3, 4, 5, 6, we display the mutation scores obtained by joining together the test cases (RP_i) and (RR_i).
Bar charts with the average of the mutation scores obtained with the tests generated by BETA in each experiment of the b2llvm and C4B case study (original, improved, and randomization).
We tried to eliminate the threat to the construct validity by including a comparison of the pairwise generation with randomly generated test data, in addition to the mutation scores obtained.
By conducting this experiment, we plan to compare the means of the mutations scores obtained by the (RR_1) and (RP_1) sets and by the (RR_2) and (RP_2) sets.
Novel missense and splicing variant mutations were potentially pathogenic, this being inferred from the score obtained from different in-silico tools and the fact that they co-segregated with the disease (Supplementary Table S4).
Afterwards, the means of the mutation scores are obtained and compared.
The mutation scores are obtained by adding sample mutation scores over all samples followed by normalization to 1.
The total score obtained ranges from 0 8.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com