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Therefore, we retrospectively analyzed repeated sweat chloride values obtained in patients with G551D mutation(s) assigned to placebo in an ivacaftor interventional trial.
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The phenotype described here for amylopectin structure and amylose content can be definitively assigned as a result of the Atss2 mutations, as opposed to any other unidentified mutation(s) present in the T-DNA insertion lines.
GEMA_r01.java has several advanced features already build in including the availability of multiple environment option where each mutation is assigned a selection coefficient vector with coordinates representing scalar s values specific for each environment.
By assuming that the vast majority of observed mutations were single nucleotide changes within a codon, each mutation was assigned to the NS (nonsynonymous) or S (synonymous) class of mutations, and the average z-score of each class was computed for every codon.
Cooperation could be acquired through mutation or assigned in advance.
Hence, profiles which differed from one another by only a single mutation were assigned to a single individual.
Variants arising by mutation were assigned effect sizes.
When a given classification algorithm produced posterior probabilities of mutation status, we assigned each variant's mutation status according to the higher posterior probability (Weka's default behavior).
Upon generation of a mutation, GEMA assigns a selection coefficient (s parameter) to the mutation using a user-defined s distribution.
Then random mutations are assigned to each by the spin of a "wheel of fortune", while changes in the environment are represented by the changing height of the canopy.
Bulk of RMA DNA was used as a reference against which mutations were assigned.
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