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As could be observed, when cytological material was obtained from primary tumors, the mutation results for histology and cytology were concordant in all cases where both results were determined.
The mutation results for the 20 specimens selected for challenging specimen attributes are depicted in Supplementary Table 1.
Inclusion requirements were the following: study populations composed entirely of PCP patients; mutation results for all patients, regardless of sulfa prophylaxis exposure; and treatment outcome results for all patients, regardless of mutation status.
Although the mutation results for prophages indicate that prophages are not transcribed, because most prophages in the genome of ATCC948 are incomplete, further investigation is required to determine whether the rate and spectrum of spontaneous mutations reflect that of more complete prophages or prophages in other organisms.
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The predictive value of the line probe rpoB mutation result for MDR-TB was 91%95%5% confidence interval 92 100).
The positive predictive value of the line probe rpoB mutation result for rifampin resistance was 94%9595% CI 88 100), and the negative predictive value was 96%9595% CI 92 100).
We have reported genetic thrombophilia and JAK2 mutations results for 271 primary OLT recipients.
Since, 854 lies in the contact region of erlotinib but not close to ATP, this mutation results in reduced affinity for erlotinib while maintaining its kinase activity.
This G>A mutation results in a lysine substitution for glutamate at position 17 (E17K) and leads to a PI3K-independent activation of AKT1.
This mutation results in a higher barrier for attack at C2 and thus the more favorable C1 attack (13.9 and 17.5 kcal mol−1 for attacks at C1 and C2, respectively) leads to an increased S, S selectivity.
Samples that still did not provide satisfactory mutation screening results for at least 80% of the concatenated MRN coding sequence were excluded from further analysis.
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