Sentence examples for mutation result in from inspiring English sources

The off-target mutation result in part from Cas9-mediated double strand break (DSB) of DNA.

However, in this assay the deletion of the ORC-binding site, the deletion of FUN30, or the double mutation result in almost the same growth, indicating possible epistatic relationship between ORC and Fun30 at this locus.

FAD-linked mutations have also been found in APP, and depending on the mutation result in increased β-secretase processing, increased Aβ42/Aβ40 ratio, increased propensity of Aβ to form fibrils, or decreased proteolytic clearance of Aβ peptides [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20].

Some mutations, such as the common ΔF508 mutation, result in inability of the encoded protein to reach the plasma membrane.

Neither does this mutation result in the random scattering of cells that is observed for the dentate granule cells.

Both mutation result in constitutive activation of PI3K/AKT signaling and contribute to cellular transformation [ 11, 12].

Mutation results in sustained activation of β-catenin protein, resulting in uncontrolled hepatocyte proliferation.

Map-based cloning of the mutation resulted in the identification of the YGL138 t) gene.

These observations indicate that the asl3 mutation results in abnormal development of the chloroplasts.

RNA analyses showed that this mutation results in an in-frame loss of exon 9.

Objectives: We aimed to investigate if this mutation resulted in excessive BKV excretion in HC patients.