Sentence examples for mutation restored the from inspiring English sources

Remarkably, a one-nucleotide mutation within the 5′UAR was correspondingly co-selected; the 5′UAR mutation restored the base pairing with the 3′UAR mutation.

Back mutation restored the colonization ability.

All plants tested were more susceptible than the resistant Kas-1 ecotype and complementation of the atl9 mutation restored the wild-type defense phenotype (data not shown).

The N146A mutation restored the interaction with the complex, while the W155A mutation did not (Fig 3C), indicating that the protruding tryptophan is an essential residue for interaction with the complex.

Notably, the I539T mutation restored the wild-type NBD1 pattern in ΔF508: both protease resistant bands of ∼25 and 27 kDa that had been lost in ΔF508 NBD1 returned upon mutation of I539 to Threonine (Figure 4A, ◂).

Comparing longer exposures of the 100 µg/ml ProtK treatment of the NBD1 molecules revealed that only the I539T mutation restored the ∼17 kDa protease resistant band that had been lost in ΔF508 NBD1, whereas G550E had no measurable impact (Figure 4B, ).

AO therapy could be used in specific CF cases to alter splicing to skip an exon containing a nonsense or frameshift mutation, restoring the reading frame, assuming the resultant isoform retained better function than the mutated protein.

Importantly the inhibition of the RAS pathway in cells harboring BRAFV600E mutation restores the LKB1-AMPKα pathway by permitting the re-association of the LKB1-AMPKα complexes.

The introduced BZcon1 gene fully complemented the BZcon1 null mutation, restoring the capability for sporulation.

We further find it exceedingly unlikely that the cdc3 (D210G) mutation restores the ability of Cdc10(D182N) to bind and hydrolyze GTP.

One G418-resistant complementary transformant, C113-2, fully complemented the CAN13 null mutation, restoring the capability for sporulation (Table 1 and Figure 4B).