Sentence examples for mutation responded to from inspiring English sources

In the drug's earliest trial, nearly every patient whose tumor cells contained the B-RAF mutation responded to the drug.

The patient harboring this mutation responded to therapy (PR).

The laboratory selection experiment found that L1014F mutation frequency, but not L1014S mutation, responded to deltamethrin selection, suggesting that the L1014F mutation is the key mutation conferring resistance to deltamethrin.

Both patients with a KCNJ11 mutation responded to oral sulphonylurea.

None of the patients bearing BRAF mutation responded to the treatment, in comparison with 24 32%) of 74 patients with BRAF wild-type disease (P=0.016; Table 3C).

Thus far, few studies have shown EGFR mutation in SQCLC, and patients with activating EGFR mutation responded to TKIs treatment [ 11].

Anecdotal reports of patients with diverse cancers and HER2 amplification or mutation responding to anti-HER2 agents have been published [ 15– 18], implying a potential role for anti-HER2 agents outside of breast and gastric cancer.

None of the patients with tumors exhibiting BRAF mutations responded to an EGFR antibody treatment, wheras none of the responders to the treatment had BRAF mutations [ 38].

As expected, three of four PDX that were HR deficient due to BRCA1/2 mutations responded to rucaparib in vivo (Table 1, Supplementary Data 2).

Four EGFR FISH+ patients with KRAS mutations responded to cetuximab therapy.

None of the nine tumours with KRAS mutations responded to EGFR-TKIs (Pao et al, 2005b).