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Importantly, the Tyr c -2 J mutation rescued all observable Tyrp1 b – and Gpnmb R150X -associated iris phenotypes in double-congenic B6.
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In CFTR exon 12, ExSpeU1 cf11 rescued all 5′ss mutations with different efficiency.
Under our conditions, expression of Gem1 mutants harboring abrogating mutations in either EF-hand I or II motifs or both rescued all mitochondrial phenotypes in gem1Δ cells to a similar extent as wild-type GEM1.
We found that an hsp83 transgene expressing the wild-type protein rescued all but two of the phenotypic effects of the GE24185 mutation.
Minigene experiments with the CFTR exon 12 showed that all mutations were rescued by the corresponding complementarity U1 snRNAs.
This tendency is opposed by rescue mutations, all with growth rate r1 > 0, which comprise a fraction Φ of the overall genomic mutation rate U.
M136I is also modestly stabilizing, and partially rescues all three individually deleterious mutations.
Only the 2K-V9M mutation efficiently rescued viral growth by promoting vRNA replication.
Furthermore, as shown in Fig. 6c, d, the correction of the FUS mutation completely rescued the ligation defect.
Myelin compaction was also rescued in all strains.
Hmr mutations rescue hybrid males with all three sibling species of D. melanogaster but rescue best with D. mauritiana compared with D. simulans and D. sechellia (Hutter and Ashburner 1987).
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