Sentence examples for mutation reflects the from inspiring English sources

Thus, the ΔΔ Go of the R58A mutation reflects the net free energy change of disrupting both these interactions.

On the other hand, assuming that the expected phenotype of a double mutation reflects the additional effects of the single mutations, E-MAP, an extension of SGA, gains power by identifying positive as well as negative interactions, which, in this case, would indicate that the double mutant is healthier than expected.

The frequency of OMIDI pairs in the EGFR gene is approximately 10-fold greater than in the TP53 gene (and the one OMIDI pair in the TP53 gene does not result in a net in-frame mutation), reflecting the more frequent selection of mutations that alter, rather than delete, EGFR protein function.

Yet does this starting point, appearance of crippling mutation, reflect the starting point of natural evolutionary scenarios as we understand them?

The milder phenotype of dominant mutations reflects the subtle KATP channel defect in comparison with recessive mutations, which lead to defects in channel biogenesis, trafficking and assembly.

However, our suggestion was untested at that time, and presumably the lack of effect of these mutations reflects the fact that the energetic costs of desolvating the carboxyl of the aspartic acid and the hydroxyls of the ribose offsets the contribution to binding of the hydrogen bonds that the aspartic acids make with AXPs.

The DNA samples derived from unmutated HA plasmid show a low frequency of apparent mutations which are almost exclusively composed of single-nucleotide codon changes the frequency of these apparent mutations reflects the rate of errors from the PCR amplification and subsequent deep sequencing.

Benign mutations (as the combination of silent and LoFI) mutations reflect the background mutation rate of each gene.

In the absence of recombination, the NRY passes mostly unchanged from father to son and observed mutations reflect the evolutionary history of the Y chromosome.

About 30% of all reactions and 19% of included genes were lethal mutations reflecting the inability of the perturbed network to synthesize essential components.

Manning also identified the inefficiencies existing in polyclonal populations that prevent sweeping of advantageous mutations, reflecting the reproductive isolation of clonal lines [ 17].