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The observed decrease in mutation ratios was expected for all time-windows as the high ratios of external branches also contributed to the ratios of the older clades (Figure 5).

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The mutation ratios were calculated by dividing number of mutant calli or shoots by the total number of transformed calli or shoots.

After the removal of the external branches the mutation ratios were still higher for the younger clades.

The non-synonymous to synonymous and RNA to synonymous mutation ratios were also presented as Ka/Ks or Kri/Ks values that gave the relative rates with respect to the rate of synonymous substitutions.

R/S mutation ratios were calculated for the total VH segment, FRs and CDRs (Table 2).

Indeed, synonymous polymorphic sites are consistently fewer across genes within the Maine population compared to the Georgia population, and chi-squared tests of 2 × 4 contingency tables indicate that the Georgia mutation ratios are significantly different from those of both northern populations (p > 0.01 for both comparisons), but northern ratios are not different from each other (p = 0.77).

Therefore, the mutation ratio was 25.7%% (Fig. 1) for TE genes.

In Y1 the UroVysion test was negative for all patients, and the FGFR3 mutation ratio was quite high (38%).

Instead of SLT, the mutation ratio was calculated using base-pairs screened and the number of mutations detected in fugu Mstn gene by HRM analysis (Table  3).

In their study, the induced mutations were investigated using growth-related genes (Igf-2a, Igf-2b, Mstn-1, Mstn-2, Fst-1 and Fst-2) and the estimated mutation ratio was around 0.41%.

In population genetic model studies of bacteria it was shown that phenotypically distinct clusters can only evolve if the recombination mutation ratio was below a certain threshold [ 3, 4].

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