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Lower mutation rates tended to converge faster, but to a lower fitness value.
The robustness of these organisms was computed and an analysis of variance showed that, consistent with previous work [ 27, 28], high mutation rates tended to favor the evolution of robustness (P < 0.001), whereas population size had no direct effect on robustness (P = 0.818), but and indirect one conditional on mutation rate (interaction term, P < 0.001).
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Moreover, recombination frequencies and mutation rates tend to increase under stressful conditions [35], [36], [37].
Alternatively, mtSNPs can be selected according to their mutation rate; mtSNPs with the highest mutation rates tend to yield the maximum diversity values.
High mutation rates tend to decrease the stability of a protein.
Nonetheless the choice of a method strongly affects the results, as low mutation rates tend to less discriminate the genetic differences, whereas high mutation rates tend to increase the number of clusters considered [ 14].
However, we still found that taxa with lower mutation rates tend to have elevated numbers of edited sites.
Selection rates dependent of mutation rates tends to survive allele A. But the evolutionary process is dominated by the irreversible mutations, the fittest class A loses.
It is noteworthy that mutation rates tend to be lower in all of the taxa where the rate of removal of edited sites can be explained exclusively by the synonymous rate of C-to-T mutations.
> -wrap-foot> If genes with higher mutation rates are more likely to lose introns, and intron loss dominates intron gain, one could expect that genes with higher mutation rates tend to have fewer introns.
Previous studies have found either that mutation rates tend to increase approximately linearly with distance from the origin of replication [ 42– 44] or peak at intermediate positions between the replication origin and terminus (Salmonella enterica [ 45], E. coli [ 5]).
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