To assess the sensitivity of our assay, we quantified mutation rates for alleles of 33 mutator genes.
Based on the mutator MA line data, we calculated the context-dependent mutation rates for the center (focal) nucleotide of each of the 64 possible nucleotide triplets.
The initial crossover and mutation rates for GA and IA were all set as 80% and 55 %.
By doing so he ignores fifty years of progress in molecular clock techniques in general and the study of mutation rates for cytochrome c in particular.2.
We showed that the mutation rates for the majority of these CNVRs are at the order of 10−5 per generation, consistent with experimental observations at individual loci.
An explanation of these features is proposed, which involves the identification of three phases of search behaviour, where each phase is identified with an interval of mutation rates for non-adaptive evolutionary algorithms.
Single-strand DNA viruses are an exception to this rule, however, as mutation rates for these genomes can approach the extreme of the ssRNA virus case.
Mitochondrial data were used in this analysis because mutation rates for the hypervariable region are better known.
Data on mutation rates for TGFBR2 exon 3 and ACVR2 exon 10 (Table 1) showed similar results.
Greater inference bias as a function of MCU reflects a combination of differences in fixation probabilities and per locus mutation rates for pu and up changes.
One of the most interesting results of the present study is the variability in the reversion and mutation rates for each HLA-associated variant.
