Sentence examples for mutation rate this from inspiring English sources

However, due to a high mutation rate, this virus is capable to develop resistance to existing drugs causing the treatment failure.

Given the PNG2 mutation rate, this is unexpected, unless in different genetic backgrounds selection favors different alleles.

We expect that, at some high mutation rate, this fidelity drops significantly enough that the polymerase rate inherited from one generation to the next is not significantly distinguishable from a randomly assigned value.

After including confidence intervals on mutation rate, this corresponds to a point estimate of Ne equal to 2632 with 95% density in (0, 40 000).

At the known yeast mutation rate, this would result in roughly 2-3 mutations pre haploid genome content (or as many as 12 mutations in their strain as it is tetraploid).

A nucleotide site with mutation frequency greater than the threshold therefore suffers more mutation than expected based upon the overall mutation rate; this method allows one to distinguish RIP-like hypermutation patterns from random mutation.

Based on known phage mutation rates, this piece of viral DNA seems to have dispersed sometime in the past 2,000 years5.

However, when the markers have heterogeneous mutation rates, this quantity does not correspond to the heterozygosity of the average mutation rate (or to any other single mutation rate).

In contrast, for high mutation rates, this cost can be brief or absent.

As viruses typically have short genomes and exhibit high mutation rates, this regression step, successfully applied in metagenomics [ 22], was thought to reduce bias in the data.

The tRNA-Tyr alleles with low mutation rates to ochre suppressors are oriented such that adenine incorporation opposite 8-oxo-guanine will occur on the lagging strand, whereas for the tRNA-Tyr alleles with high mutation rates this will occur on leading strand and have a greater potential of escaping mismatch repair.