Sentence examples for mutation rate there from inspiring English sources

Exact(3)

When genome positions have the same mutation rate, there is not enough diversity in the predicted mutation spectrum.

Regarding the mutation rate: there is more TE activity in humans than in chimpanzees (see Table 2 and Britten, R.J. PNAS, 107: 10745-10748).

Since there is no discontinuous transition from sites with zero mutation rate to a high mutation rate, there is always a class of sites with a minimal mutation rate fully conforming to the infinite sites model, and this class of sites is precisely the one most valuable for phylogenetic inference.

Similar(57)

Consistent with effective selection against higher mutation rates, there are no reports to date of mutator strains at substantial frequencies in natural yeast populations, despite the low rates of outcrossing inferred in such populations [ 43, 44].

An explanation that fits the experimental data is now offered: at realistic mutation rates there is coexistence between fit genotypes that have unfit neighbours on the adaptive landscape, and less fit but more mutationally robust (sometimes called 'flat') genotypes.

Assuming reasonable values for the cellular division, death, and mutation rates, there must be at least k = 1000 mutations that confer resistance against only one drug for triple combination therapy to somewhat improve the chances of treatment success.

Therefore at high mutation rates there is survival of the flattest and not survival of the fittest.

While there have been numerous measurements of Y-STR mutation rates, there is, as discussed above, controversy about which rate should be used in evolutionary studies.

Disruption of translesion synthesis results in a 4.8-fold reduction in the mutation rate at the late-replicating locus with the high mutation rate; for the late-replicating region with the lower mutation rate and the early-replicating regions with low mutation rates, there is no significant effect of REV1 deletion (fig. 7).

Okay, there is likely to be variation with some life history parameters - we probably can't have the combination of very long lived species combined with very high mutation rates there might be too many mutations between parents and their offspring?

In order to arrive at the values of πsilent observed in this study, N g would have to be higher for the nuclear genome than for the mitochondrial genome (again, assuming equal mutation rates); there are a few reasons why this might be the case.

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