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The results show that, the mutation rate seems to be taken in the range of 4 6% and the number of individuals in each generation should be at least 60.
A high mutation rate seems to be the case for this region in general, as indicated in Figure 6.
Although microsporidian genomes appear to have had little rearrangement, the nucleotide mutation rate seems to be high in this group of organisms [ 19, 20].
Taking our data together with previously published findings, the effect of smoking on the EGFR mutation rate seems to be independent of ethnic origin (Table 4).
Since the mutation rate seems to be random across the genome, it was difficult to estimate the mutation rates of SSRs in different categories, i.e. SSR types or functional regions.
However, based on currently available evidence, it has been estimated that about 13% of the human genome varies in copy number and the per-locus mutation rate seems to be higher for CNVs compared to SNPs (Stankiewicz and Lupski 2010).
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The mutation rate seemed to correlate with the level of template dilution, with over 1 mutation per kb when the template concentration was under 1 pg/μl.
This variation is much larger than the variation in synonymous substitution rates, so an explanation involving variation in mutation rates seems unlikely.
As Figure 8 shows, for a fixed mutation supply rate, smaller populations with higher mutation rates seem to have a slight advantage.
The relative mutation rates seem to indicate that the changes in mating system have not led to major changes in the mutation machinery.
Such high mutation rates seem to be supported by our best approximation of the genetic architecture in the Amazon molly (many approximately codominant mutations of small effects in a genome with very low levels of mitotic recombination lead to an effective doubling of U sdm as shown in the Equal-Contribution-Model in Table 1 and discussed in the Models section below).
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CEO of Professional Science Editing for Scientists @ prosciediting.com