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The organisms were characterized by their strategies of interacting with the environment and gathering resources; their fitness, defined as the amount of food gathered, was found to be optimized for an intermediate mutation rate, where the mutation rate represented the rate at which strategy elements were selected from a pool of possible behaviors.
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This mutation rate represents a phenotypic rate, rather than genetic mutation rate, and can be thought of as arising from multiple genetic sources.
It should be noted that the recorded AZFc mutation rate represents a conservative estimate since it refers solely to changes in the number or order of the reference sequence amplicons.
For each replicate, 30 random coalescent trees were generated, each with 15 individuals assuming a constant population size with N e μ = 2.0 (where N e is the effective population size of chromosomes and μ is the mutation rate representing the number of mutations per microsatellite locus per generation).
For each replicate, 30 random coalescent trees were generated, each with 15 individuals assuming a constant population size with Ne μ = 2.0 (where Ne is the effective population size of chromosomes and μ is the mutation rate representing the number of mutations per microsatellite locus per generation).
Mutation rates represent probability of a mutation per nucleotide.
Methods using this approach, termed 'frequency-based' methods, rely on an estimate of a background mutation rate which represents the rate of random passenger mutations.
The net mutation rate therefore represents a balance between the error-prone DNA replication process and the highly efficient error-repair mechanisms.
However, this approach may not detect mutations at single TALEN sites where the restriction site is not disrupted; hence, our results may under-represent the actual mutation rates present in individual animals.
The mutation-scaled migration rate represents the importance of within-population variation derived from migration events relative to mutation [ 23].
The backward rate represents the rate of back mutation that overcomes single point mutations, the rate of insertion/deletion that reconstitutes a previous indel, the rate of excision of an IS, and the rate of gene conversion and lateral gene flow.
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