Sentence examples for mutation rate relating from inspiring English sources

In HNPCC patients aged < 49 years the mean stem cell mutation frequency was significantly lower than in the slightly younger group of patients with Crohn's disease (0.8 +/- 0.9 x 10 -4) vs 3.5 +/- 3.3 x 10 -4), P < 0.01), probably reflecting an increased mutation rate relating to chronic mucosal damage in Crohn's disease.

Pathways in HER2+ are a mixture of TP53 (mutation rate 72%) related pathways and PIK3CA (mutation rate 40%) related pathways.

Overall, the action of natural selection on mutation rate is related to population size and mutation effects.

We found no evidence of mutation rate being related to relative testes mass, which reflects sperm production rate.

The mutation rate is related to an initial repeat copy number and can even reach the value of 1 per locus per gamete per generation, meaning that the repeat copy number is changed upon every intergenerational transmission.

Such a high mutation rate should be related to the hypermethylation of these sequences (see e.g., Hu et al. 2012).

This discrepancy is reconcilable by distinguishing the mutation rate, which is related to the tempo of change at the population level, from the substitution rate, which reflects long-term evolutionary change.

Mutation rate was not significantly related to adult survival rate corrected for the effects of allometry based on a phylogenetically corrected estimate (ln likelihood ratio = 1.07, d.f. = 1, P = 0.14).

However, the frequent occurrence of 'high-curli sector derivatives' of the outbreak strain is not just a consequence of its high general mutation rate, since the closely related HUSEC041 has a similar high mutation rate but does not generate high-curli derivatives and shows stable temperature and salt regulation of CsgD.

All evolution of phenotypes results from minor increases in mutation rates of genes related to a particular stress [2] [4].

Minisatellite mutation rates were not related to longevity, suggesting a meiotic rather than a mitotic origin of mutations.