Sentence examples for mutation rate necessary from inspiring English sources

Moreover we have established a new, corrected mutation rate necessary for quasispecies formation with a higher value than the original one.

Due to the high mutation rate of HA, it is necessary to vaccinate every year, according to World Health Organization suggestions [ 20].

The ability of a population to adapt to a rapidly changing environment is directly proportional to its mutation rate [ 19], which provides the necessary phenotypic variation to allow populations to respond to novel selection pressures.

Mutation rate and generation time estimates are necessary to scale the results of the PSMC analysis.

To keep the mutation supply rate constant, it was necessary to increase the mutation rate for the small populations.

A high mutation rate in the LRR contributes to genetic variability, necessary for specific recognition of diverse pathogens [ 16].

We have to note that some genes tend to have high false discovery rate in mutation calling, for instance HYDIN, SYNE1, and USH2A [ 29] – it is an advantage of the proposed methodology is that despite the high mutation rate, none of these genes reached the significance necessary to be included in the list of putative driver genes.

It is necessary to clarify the conceptual difference between the critical mutation rate and the error threshold.

When both deleterious and beneficial mutations are present, it is necessary to explore whether an organism could evolve to an "optimum" mutation rate under these two opposing forces.

Further research will be necessary to unambiguously demonstrate the theoretically expected effect of recombination on mutation rate evolution in sexual populations.

Although thorough estimates of the mutation rate and spectrum (defined here as the rate distribution of different types of mutations at different sites) are necessary to understand many evolutionary processes (Halligan and Keightley 2009; Lynch 2010a), our knowledge of these critical parameters is limited to a handful of model organisms.