Sentence examples for mutation rate identified from inspiring English sources

This is congruent with the faster parasite mutation rate identified in the *BEAST analysis.

However, the overall mutation rate identified (20%) was similar to those found earlier in which a correlation was reported, suggesting that this is likely to be the case in this study (Ellison et al, 2005; Clifford et al, 2006; Thompson et al, 2006).

The instability of GpT identified by SNP analysis supports the prediction of an elevated G→T,T mutation rate identified by modelling and by the under-representation of GpT in human (Additional file 2: Figure S1A; ≈80% of expected value) and in other mammalian sequence datasets (data not shown).

The differences in KRAS mutation rates identified suggest that sex and tumor location influence the chance of clinical usefulness of EGFR inhibitors with a particularly low likelihood of benefit among female rectal cancer patients.

For example, sequencing and analysis of the genomes of two siblings and their parents made possible the direct measurement of the inter-generational mutation rate and identified genes potentially associated with two Mendelian disorders [ 2]; the gene causing one of these disorders was precisely identified through further exome sequencing in additional diseased patients [ 3].

One way is to define an expected number of mutations per gene, using the mutation rate, and identify genes with more mutations than an expected threshold.

Tumor driver genes are normally considered as with high somatic mutation rate, thus 156 TDGs identified without information from mutation rate are intriguing.

Several genes with lesser mutation rates were also identified (Table S4).

The contributions of factors that affect mutation rates can be identified using analyses of substitution rates.

The cost and rate of TILLING is dependent partially on the quality of the DNA being screened (how reliably the reactions work) and the mutation rate (how many alleles are identified per pooled population).

In this review, we summarize drivers of microbial diversity that have been identified, such as mutation rate and environmental influences, and discuss how knowledge gained from microbial experimental evolution studies may guide us to identify and understand important selective factors that promote intra-tumor heterogeneity.