Sentence examples for mutation rate even from inspiring English sources

This mutation rate exceeds the average mutation rate even of highly mutated adult cancers by one order of magnitude; thus, they are called 'ultra-hypermutated'. A secondary mutation in one of the proofreading polymerases δ and ε has been observed in all ultra-hypermutated cancers.

However, some genes still have an inexplicably high mutation rate even after accounting for all the previously mentioned factors.

Of the remaining genomic regions, it is remarkable that non-repetitive intergenic regions also experience a relatively low mutation rate, even lower than that of coding regions.

FST and RST differ in sensitivity when estimated on SSRs [ 65]; indeed FST can underestimate the magnitude of differentiation when populations are highly structured or are in a situation where the SSRs show high mutation rates; in contrast, RST is independent of the mutation rate, even if it has a high associated variance.

Our analysis also suggests substantial variation in mutation rates even among mutations involving the same nucleotide changes.

But when the scientists started counting the number of mutations in each tree branch, they found vastly different mutation rates, even for closely related species.

Several whole-exome or whole-genome sequencing studies consistently reported low overall mutation rates even in heavily treated CRPCs [ 9- 14].

For higher mutation rates even the POIMs assign more importance to shorter POs, but they continue to be closer to the truth than the two other approaches.

Finally, it is worth realizing that the system evolves the C-catalyst rather than the A-catalyst for higher mutation rates, even though the A-catalyst has a higher sequence freedom and, thus, is more robust against mutations.

However, several large scale whole-exome or whole-genome sequencing studies consistently reported low overall mutation rates even in heavily treated CRPCs ranging from 0.9 to 2.00 mutations per mega base [ 9, 11- 14].

As selection targets the population with the highest average growth rate (Schuster and Swetina 1988), in a fitness landscape with both steep and flat regions, the quasispecies can be distributed in the flatter parts at high mutation rates, even if the fittest genotypes there have lower growth rates.