Sentence examples for mutation rate allows from inspiring English sources

Secondly, the high mutation rate allows the identification of a large number of independent mutant families for a given gene in a reverse genetics strategy.

Since the competition is through the immune system response and given that the phase space of antigen recognition is not homogeneously covered [ 40], the HIV high mutation rate allows the quasispecies to find regions with weak immune response.

Knowing g ¯ and the mutation rate allows us to directly calculate the fate of neutral or very unfit mutations, but estimating the frequency of mutations of intermediate fitness requires additional simulations using our model.

However, several authors have posited that microsatellites represent important targets of selection because high mutation rate allows these loci to accumulate extensive variation that can be drawn upon immediately when environmental conditions change (Kashi et al. 1997; King et al. 1997; Trifonov 2004).

Mitochondrial DNA (mtDNA) is widely used in the study of domestication; its rapid mutation rate allows the accumulation of variation within the relevant time frame, and its maternal inheritance and lack of recombination mean that sequences can enter the population only by the domestication of a female animal.

However, if alleles could arise that produce large changes in mutation rate, adaptation would destabilize the mutation rate, allowing large-effect mutators to invade during periods requiring adaptation to new environmental conditions.

For all tests, the adaptive mutation rate allowed the genetic algorithm to find the global optimal solution, performing significantly better than other search methods, including genetic algorithms that implement fixed mutation rates.

The simulations obtained using distributions centered on the slow and standard mutation rate allowed us to check for which mutation rate has a higher posterior probability regardless topology (Table 2a).

Decreasing the mutation rate by 50 therefore increases the estimated age by 7. Comparing the estimations of T for the same mutation rate allowed varieties to be ranked from the most recent to the oldest.

It is clear that although increasing the mutation rate allowed a greater diversity to be sampled, it was from the sequences that carried the least number of mutations that functional variants were isolated [ 10].

These properties include the absence of recombination, low effective population size and the conservative mutation rate, allowing for primers to be designed over a wide taxonomic range [ 34, 35].