Sentence examples for mutation rate after from inspiring English sources

Cells could also acquire mutator mutations that led to an increase in the cell's mutation rate: after M mutator mutations occurred in a single cell, the cell's intrinsic per-locus mutation rate increased from μ L to μ H mutations per division.

Using this definition, we suggest two approximate formulas to estimate the critical mutation rate after which the quasispecies delocalization occurs.

For the specific case of a single peaked landscape we also find lower and upper bounds on ¯¯¯w q), which are used to estimate the critical mutation rate, after which the distribution of the types of individuals in the population becomes almost uniform.

An increased mutation rate after integration could also have contributed to sequence diversity in this region.

Therefore, we included this variable as a factor (with studies where we extracted the information on mutation rate directly from the publication being scored as 0, and studies where we estimated mutation rate after exclusion of extra-pair parentage were scored as 1) in the analyses because we could not correct all mutation rate estimates due to missing values.

(B ) Spontaneous mutation rates after complementing MutS or MutL-deficient cells with the indicated mutants.

(D ) Spontaneous mutation rates after complementing MutL-deficient cells shows that the DNA-binding ability of MutL is essential for MMR in vivo.

The analysis by Scally et al. (2012) corrected the variation in mutation rates after inference of τ and θ, simply by multiplying the proportion of μ to that of the human lineage (Scally et al. 2012).

These accelerations could be due to an increase of mutation rates after duplication, the relaxation of purifying selection due to the duplication of functional genes, the action of positive diversifying selection on one or both copies, or a combination of these factors [ 5, 25- 28].

However, we have to consider that mutant B7 was isolated after strong selection on CHP, and therefore the unbiased primary mutation rate immediately after EMS mutagenesis could have been substantially different.

However, some genes still have an inexplicably high mutation rate even after accounting for all the previously mentioned factors.