Sentence examples for mutation provides the from inspiring English sources
Loss of function in genes for genome stability and repair establishes a mutator phenotype in which a greater rate of somatic mutation provides the cell population with a vast repository of mutations in low copy.
Identification of a causal mutation provides the most definitive diagnosis for a genetic disease.
It is generally assumed that mutation provides the single source of biological diversity that fuels evolution.
Although mutation provides the ultimate source of genetic variation, it typically leads to decreased fitness.
The S83F mutation provides the most probable primary foundation for the evolution of fluoroquinolone-resistant S. Typhi.
As the hpo mutation provided the strongest relief of silencing of hph at Tel VR, we used an hpo strain as the transformation host.
Baker et al. have concluded that single mutations in gyrA gene that reduce susceptibility to fluoroquinolones (especially the S83F mutation) provide the starting point for the evolution of more resistant double mutants, which maintain the resistance, even in the absence of antibiotics.
The rediscovery of Mendel's research by Hugo De Vries in 1900 gave saltationists added leverage, since they felt mutations provided the mechanism for sudden evolutionary leaps, and De Vries' mutation theory posited speciation could even occur in a single jump.
On p. 94 he claims that assuming "accidental mutations provided the set of successive candidates on which natural selection operated to generate the history of life" makes "the outcome too accidental to count as a genuine explanation of the existence of conscious, thinking beings as such".
Often, tumors continue to depend on these so-called driver mutations, providing the rationale for targeted anticancer therapies.
That this result is only found on the rugged landscape supports the idea that the dynamics of fitness gain are highly dependent on the topography of the underlying fitness landscape, with epistatic interactions among mutations providing the critical advantage to small populations.
