Sentence examples for mutation proved of from inspiring English sources

Thus, inclusion of the CFPΔ mutation proved of no advantage for the Epac sensor.

27, 43 Importantly, the presence of this mutation proved to confer an unfavorable prognosis in active WM.

Out of these four, one mutation proved to be somatic, whereas three were also found in lymphocyte DNA, indicating the mutations to be of germline origin.

The deleterious c.1129 5923C>G mutation proved to be in cis with three intronic polymorphisms (c.483 + 18G>A, c.959 51T>G, c.680 + 139G>A) and the synonymous mutation c.1236G>A of a previously identified haplotype.

The R306C mutation proved most useful for understanding the function of the less well-studied MeCP2 C-terminus.

An Arg16 to norvaline mutation proved suitable.

A genetic difference in the UG Ba-m isolates at 5 loci out of 16 polymorphic loci examined compared to the known closest related strain (07-994-2411) from Kenya in a period of half a century could be a result of mutations and proves the ability of MLVA to differentiate strains from different localities, a finding congruent with that of Verger et al. [ 2].

Identification of such mutations has proved challenging in human, livestock and plant genetics [ 6].

While KRAS mutation has proven to be predictive of the resistance to epidermal growth factor receptor (EGFR -inhibiting thEGFR -inhibiting therapiesostic value of KRAS mutation in CRC remains unclear.

In retrospect, the 13 women without a mutation from a proven mutation family were not at high risk of ovarian cancer.

We estimated the penetrance for both breast and ovarian cancer in female mutation carriers (904 proven mutation carriers – 1442 females in total assumed to carry the mutation) and also assessed the effect on penetrance of mutation position and birth cohort.