Sentence examples for mutation proportion from inspiring English sources

The data were then normalized by subtracting the false mutation proportion from the total mutation proportion to determine the true mutation proportion at each nucleotide position (Additional file 1: Figure S2; see glossary for clarification).

Thus, the false mutation proportion subtraction accounted for many sequencing artefacts occurring around homopolymer regions.

False mutation proportion refers to the sequencing artefacts that occur by chance at each nucleotide position.

Thus, indels were only called if the false mutation proportion was less than 2.15 × 10−2.

For each mutation detected, we divided the true mutation proportion by the expected mutation proportion for a single mutation (threshold) to estimate the number of copies of that mutation in any given sample.

First, our method uses a simple false mutation proportion subtraction to minimize sequencing artefacts and alignment errors.

Comparison of the density of false mutation proportions between base substitutions (red) and indels (blue).

The average between the true mutation proportions of each technical replicate was used to provide a rough estimation of the total number of each type of mutation.

Fisher's exact tests were used to examine whether mutation proportions vary across age groups or among patients meeting different numbers of eligibility criteria.

In order to prevent outlier libraries from influencing the background reading, false mutation proportions were estimated by calculating the median rate of occurrence of each mutation type across all samples for each nucleotide position.

We are planning an additional study using cytological examination to clarify the mutation detectable proportion as a next step.