Sentence examples for mutation profiling of from inspiring English sources

The first comprehensive mutation profiling of 623 genes in 188 adenocarcinomas identified 26 significantly mutated genes, including known oncogenes (KRAS, EGFR, ERBB2, ERBB4, EPHA3 and other ephrin receptor genes, KDR, and FGFR4) and tumor suppressor genes (TP53, CDKN2A, STK11, NF1, ATM, RB1, and APC) [ 7].

We performed mutation profiling of formalin-fixed paraffin embedded tumors of multi-regional colon cancer and characterized the consequences of intra- and inter-tumor heterogeneity and metastasis using targeted re-sequencing.

The ability to perform robust mutation profiling of clinical and archival tumor tissue may promote systematic molecular characterization of "orphan" cancers, including some pediatric tumors where sufficient tissue is often lacking.

Mutation profiling of metastatic lymph nodes and their corresponding primary tumors showed that they were 89.7% concordant.

To our knowledge, this is also one of the most exhaustive analyses of mutation profiling of metastatic lymph nodes and their corresponding primary colon tumors.

Because up to 70% of the TDP pathology patients remained unresolved after C9orf72 analysis, we performed mutation profiling of the other TDP-43-associated genes GRN, VCP, and TARDBP.

The mutation profile of the viruses infecting these individuals were deduced and correlated to laboratorial parameters.

Here, we review the literature on the application of MassARRAY technology (Sequenom Hamburg, Germany) to determine the mutation profile of solid tumors from patients.

Here, we conducted comprehensive analyses for expression, somatic copy number alteration (SCNA), and mutation profiles of 1,542 RBPs in ∼7,000 clinical specimens across 15 cancer types.

Many studies have examined specific mutations in patients with resected lung adenocarcinoma across heterogeneous stages, comprising predominantly advanced/metastatic disease, but there is little data regarding the mutation profile of patients with early stage node negative disease.

We use somatic mutations to generate the mutation profiles of cancer patients.