Sentence examples for mutation profiling in from inspiring English sources

Mutation profiling in mice provides direct evidence that somatic AR variants are selected by therapy, a finding validated in human metastases from distinct treatment groups.

We report the implementation of a genotyping and validation algorithm that enables robust tumor mutation profiling in the clinical setting.

In summary, this study represents the first large-scale application of the OncoMap platform for tumor mutation profiling in the clinical and archival setting.

To facilitate cancer gene mutation profiling in clinical tumor specimens, we developed OncoMap, a panel of genotyping assays that assessed 396 unique mutations in 33 cancer genes.

In a previous report of JAK2 mutation profiles in a series of >10,000 patient samples, we described detection of a novel deletion of JAK2 exon 14 (Δexon14) along with other JAK2 mutations in exons 12 through 15, using bi-directional mRNA sequencing technology [7].

The mutation profile in the TP53 gene can indicate the potential cause of the mutation.

This heterogeneity may reflect different cells of origin and/or different mutation profiles in these cells.

47 Hence, further studies are needed to clarify mutation profiles in NK/T-cell lymphoma.

This underscores that the gene expression data is more informative than patient mutation profile in locating ovarian cancer genes.

This paper shows a change in mutation profile in the presence of ribavirin in humans concomitant with a decrease in viral load.

The somatic mutation profile in lung adenocarcinomas lacking targetable EGFR or KRAS mutations or ALK rearrangements in never-smokers is highly complex.