Sentence examples for mutation prevented the from inspiring English sources

Consequently, the mutation prevented the correct localization of the channel in the cell membrane [14].

The suppressor mutation prevented the regulatory subunit from binding to the kinase domain, thereby allowing the kinase to remain constitutively active.

These data therefore suggested that the p.Val194Asp mutation prevented the proper trafficking and secretion of matrilin-3, whereas as the p.Glu252Lys polymorphism did not.

This indicates that phosphorylation of Ser may be a prerequisite event for phosphorylation of Ser or alternatively the S326A mutation prevented the upstream kinase(s) from phosphorylating the Ser residue.

Ashlyn's mutation prevents the gene from making the channel, and the electrical impulses are never produced.

Further for LZ+ MYPT1 isoforms, an S668A mutationtation prevents the PKG mediated, Ca2+ independent activation of MLC phosphatase.

The G2A mutation prevents the N-terminal myristoylation of Nef to disrupt most of its membrane association which is required for many Nef activities.

How the T22M mutation prevents the nuclear localization of overexpressed FBXO7 is unclear, but the mutation might affect the interaction with other proteins which are crucial for the nuclear import of FBXO7.

The absence of expression of RBM44 by Western blot and immunofluorescence using an antibody N-terminal to the region deleted confirms that our mutation prevents the expression of RBM44 and confirms that the mutant allele is null.

This mutation prevents the formation of the trihydroxyphenylalanine quinone (TPQ) cofactor.

70 This mutation prevents the binding of vismodegib to SMO, thereby leading to resistance.