Particularly, one SMG (ie, FAT4) exhibited mutation prevalence of >10% and two SMGs (ie, DOCK2, CDH10) mutated at frequencies of >7%.
Three novel recurrently mutated genes, namely CDH10, FAT4 and DOCK2, were identified to exhibit high mutation prevalence in the Asian CRC cohort.
In this study, the relationship between lesion growth and mutation prevalence within a lesion was investigated.
To evaluate the mutation prevalence and phenotype in genes involved in the ocular retinoid metabolism.
However, somatic mutation prevalence did correlate significantly with microsatellite length.
We have presented estimates of mutation prevalence, and described infections as harbouring two, three or more mutations.
Overall these studies suggest that 816 c-kit mutation prevalence is high in adult patients and low in pediatrics patients.
For the purposes of this study, we analyzed mutation prevalence rates only within subtypes A, B, C, D, F, G, CRF01_AE, and CRF02_AG.
In conclusion, the extensive mutation frequency data summarized in this paper provides a useful context in which mutation prevalence data from population-based surveillance studies of transmitted resistance can be interpreted.
This method is able to detect mutations as well as known SNPs, even in genomic regions with a low mutation prevalence rate in the range of 5% or perhaps lower.
Complex relationships between somatic mutation prevalence and transcription were detected.
