Sentence examples for mutation positions in from inspiring English sources
However, the mutation positions in this variant are in a registration that disrupts the three-strand β-sheet rather than directly blocks β-augmentation.
Finally mutations contained in this list were manually verified using Tablet Genome viewer [ 54] by looking up the mutation positions in the BAM files generated by gsMapper.
The routine tested 22 MHC genes coding muscle and non-muscle isoforms and identified 89 missense mutation positions in the motor domain with 10 already implicated in heart disease and another 8 lacking sequence homology with a skeletal MHC isoform for which a crystallographic model is available.
For the intramolecular correlated mutation analysis, correlated mutation positions in a given protein were compared with the homologous positions in all other proteins, and these pairs were either designated 'conserved' correlated mutation if they showed a correlated mutation as well, and 'non-conserved' correlated mutation if they did not.
Of the remaining 11 genes positioned downstream of both replication origins, 9 are never involved in gene rearrangements and have very similar mutation positions in both modified and normal genomes; on average, these genes shift less than 70 bp (fig. 3).
There are in total 64 conserved groups of correlated mutation positions in the interacting protein pairs (i.e. correlated mutation positions that are observed in more than one pair of interacting proteins), whereas there are only 49 such groups in the non-interacting protein pairs.
We investigated potential correlations between mutation position in a given mutator allele and a variety of functional features of the genome.
Furthermore, hierarchical cluster analysis detects systematic relationships between organ involvement in laminopathies and mutation position in the LMNA genomic sequence.
No clear correlations were found with mutation type in both PKD genes or with mutation position in PKD2 gene.
The CORE-UK cassette (COunterselectable REporter KlURA3 and kanMX4) was first inserted at the candidate mutation position in each target gene (SSN2, TUP1, or ROX1 ) by homologous recombination.
We characterize the location of the evaluated mutation position in protein sequence and structure (eg, buried, exposed, secondary structure element, conserved region, part of the epitope).
