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b Result variation with mutation percentage for JAYA.

Open image in new window Fig. 5 a Result variation with mutation percentage for TLBO.

This is clear from Fig. 5a, b which shows the variation of results obtained to some of the difficult problems solved by varying the mutation percentage for TLBO and JAYA, respectively.

Firstly, the true mutation percentage and false mutation percentage for the reference genes at all quality scores were calculated and were used as reference to set the mutation detection parameter (Table  5).

When corrected for mutated single samples, the mutation percentage is 39%, still slightly higher than reported.

A comparison was also performed using one-point and two-points crossover operator and the results of a sensitivity study for different mutation percentage are also showed.

For each mutation LOD, the associated mutation percentage was estimated by fitting a non-linear model between ∆Ct values and mutant percentage.

Mutation percentage: 70%.

Average mutation percentage was estimated by densitometry.

About 90.8% CGC genes show somatic mutations (the corresponding percentage for HI-CGC common genes is 97.8%).

In one meta-analysis of 338 transmitted point mutations, for some mutations the percentage level of mutant mtDNA tended to increase with transmission, and for others the level seemed to decrease [37].