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We show that the pairwise (residue-residue) interaction terms of the statistical model are necessary and sufficient to capture higher-than-pairwise mutation patterns of natural kinase sequences.
HIV-1 genotypic resistance test (GRT) has been widely used to monitor HIV infection but only few reports revealed the mutation patterns of non-B HIV-1 subtypes.
After calibrating the model to multiregional and single gland data from 19 human colorectal tumors using approximate Bayesian computation, we examined the role of early tumor cell mobility in shaping the private mutation patterns of the final tumor.
Furthermore the user can investigate mutation patterns of interaction partners of genes of interest.
However, they did not go further to examine the mutation patterns of TSGs and OCGs.
Specifically, we reconstructed the phylogenetic relationship and investigated the distribution and mutation patterns of virulence determinants among 20 local isolates.
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This study describes a unique mutation pattern of VP28 gene of circulating WSSV in South-West region of Bangladesh.
The mutation pattern of the spermatozoa suggests a unique mutagenic process in the male germ line both spontaneously and following B[a]P-exposure.
The neighboring residues of a given residue play an important role in shaping the mutation pattern of the residue.
This study presents such an attempt to explore the mutation pattern of a bacterium by ultradeep sequencing.
In previous studies, the mutation pattern of gyrA-S83L/D87N gyrA-S83L/D87Ne related to levofloxacin resistance, wasreashown single mutotion gyrA-S83L was not.
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