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The effects of selection on the observed mutation patterns are most pronounced in relatively slowly mutating, non-CpG sites.
This, in turn, indicates that multifactorial studies on mutation patterns are necessary to uncover mutation processes in insect mitochondrial genomes.
Moreover, the observed mutation patterns are not accounted for by known patterns of DNA methylation in fungi.
Although these studies have demonstrated that cancer cell subpopulations with different mutation patterns are present in most solid tumors, there were several technical limitations.
In the constant model, it is required that mutation patterns are temporally constant in a genomic region: that is, the constant model assumes that initial GC content-specific (or rather position-specific) mutation patterns last forever.
In a comparison of genic SSR variations using homologous P. tomentosa and P. trichocarpa sequences (Table 2), we identified both repeat motif variations and mutations in the flanking sequences in most markers, and this shows that microsatellite mutation patterns are often complex in cross-species amplification.
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However, the influence of most mutator alleles on mutation patterns is not understood at this level.
This evolutionary history together with the striking mutation patterns is indicative of a putative neofunctionalization event that took place late during AR-B evolution It is tempting to link this neofunctionalization event to the plasticity of sex determination in Percomorphs.
Differences between the organs with respect to the spontaneous mutation patterns were observed.
The mutation patterns were listed in Table 2.
A total of 25 QRDR mutation patterns were found (Table 3).
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