Sentence examples for mutation or variation from inspiring English sources

Thus Ernst Mayr, the dean of post-World War II biology: "When it is said that mutation or variation is random, the statement simply means that there is no correlation between the production of new genotypes and the adaptational needs of an organism in the given environment" (Mayr 1998, 98).

It is obvious that mutation or variation will occur either in gene or m-RNA or protein level or in all the three levels to confer disease phenotypes.

"Do you renounce or deny your warped dialect, or do you absolutely want to hold on to it at any cost and parade your own variation or mutation of it?" he asks, citing the example of the pianist Glenn Gould.

Genetic factors include variation or mutation in genes involved in parathyroid hormone signalling.

The cell lines provide a framework for comparative molecular genetic studies investigating the genomic landscape by gene expression, copy number variation or mutation analysis.

The process of identifying a variation or mutation anywhere in a DNA sequence begins with mapping the sequenced DNA of interest to a reference human genome sequence.

For all projects aimed at discovery of mutations or variation, it is critical to follow-up with validation of the variants called, either by sampling to determine the rate at which calls are correct, or to confirm which exact changes are real rather than art factual.

DNA repair must be accurate to preserve genome stability for long-term cellular viability; genetic instability is characteristic of cancer cells, and may be due, at least in part, to mutations or variation in genes that function to ensure DNA integrity [ 37].

Nucleotide changes known as mutations or variations can lead to either gain-of-function or loss-of-function of oncogenes and tumor suppressor genes.

Mutation data are converted into a matrix with rows as subjects (n mut = 954 ) and columns as genes containing mutations or variations (500 genes).

Previous studies have already suggested that mutations or variations in the nucleotide sequence of the GLP-1 receptor gene determine the magnitude of intracellular postreceptor signaling (13– 13).