Sentence examples for mutation or level from inspiring English sources

The symbol ↑ indicates increased frequency (mutation) or level (methylation) in MSI.

The symbol ↓ indicates decreased frequency (mutation) or level (methylation, gene expression) in MSI.

In this study, PIK3CA mutation, KRAS mutation, or PTEN level by IHC did not predict outcome.

In contrast, mutation or reduced level of Smad4 in colorectal cancer is directly correlated to poor survival and increased metastasis.

In a multivariate analysis (logistic regression), L2/L3- TP53/ CHEK2 mutations or low level ATM expression was also confirmed to be significantly associated with resistance to therapy (overall test of the model, P = 0.010).

Notably, the different models all revealed a statistically significant correlation between defects in the p53 pathway (defined as L2/L3- TP53/ CHEK2 mutations or low level ATM expression) and therapy resistance defined as PD on treatment (P-values varying from 0.001 to 0.027; Figure 2B).

We aim to find the best framework configuration (generation and population, mutation levels, crossover levels) according to given data set context.

Which genetic framework configuration (generation and population, mutation levels, crossover levels) did report the best performance when compared to the baseline exhaustive framework?

In compound heterozygotes for a GAA expansion and a point mutation or deletion, frataxin levels were plotted against the length of their single GAA repeat in both buccal cells and whole blood (Fig. 4A and B) and the best-fit line from Figure 1A or C (frataxin levels in buccal cells or blood for subjects homozygous for GAA repeat expansions) was overlaid on the point mutation data.

Pathological information on mutational status of RTK and p53 mutations or expression levels of key signalling molecules, such as EGFR, HER-2 and HIF-1 expression, should also be obtained to select appropriate patient populations.

However, high levels of 2-HG were not associated with somatic mutations or expression levels of IDH1 or IDH2.