Sentence examples for mutation or depletion from inspiring English sources

Mutation or depletion via RNA mediated interference (RNAi) of the C. elegans ERK ortholog MPK-1 and other components of the ERK cascade results in sterility characterized by the failure of germ cells to progress through pachytene [24], [26].

In contrast, mutation or depletion of most other members of the SSU processome complexes causes decreased 18S rRNA levels without affecting the levels of the 25S or 5.8S rRNA.

Sequence analysis, combined with knowledge about the rRNA processing intermediate that accumulates upon mutation or depletion of a ribosome assembly factor can often provide a starting point for analyzing the role of an enzyme in ribosome assembly (nucleases, methylases, or helicases).

Specifically, its mutation or depletion prevents normal gene inductions by, and renders worms sensitive to arsenite and tBOOH.

However, mdt-15 mutation or depletion also shortens the lifespan of wild-type worms (Taubert et al., 2006).

Mutation or depletion of TTBK2 reduced BGT1 and SGLT1 stability in the cell membrane and resulted in loss of GABA or glucose transport capacity in Xenopus oocytes.

We demonstrated that three independently isolated hif-1 mutations or depletion of hif-1 by RNAi extended C. elegans lifespan.

This finding aligns with data that suggests blunted DNA repair, stemming from Fan1 mutations or depletions, leads to interstitial nephritis [14], a condition associated with proteinuria and renal hypertrophy [48].

Mutation or PIP2 depletion changes juxtamembrane interactions with the bilayer.

In (D and E ), cell lysates were resolved on 10% Phos-tag gels and analyzed by western blot, where 'asterisks' denote bands corresponding to IST1 phosphorylated species, sensitive or insensitive to the 4SA mutation or ULK3/CHMP4C depletion.

We investigated a cohort of 52 patients with combined respiratory chain deficiency without causative mitochondrial DNA mutations, rearrangements or depletion, to determine whether a defect in mitochondrial translation defines the pathomechanism of their clinical disease.