Sentence examples for mutation onto the from inspiring English sources

To determine if mFasL also accelerates RGC degeneration in this spontaneous model of glaucoma, we backcrossed the ΔCS mutation onto the DBA/2J background.

To address this, we generated a caps trn double null mutation, capsDel1 trn28.4, by using P-element induced male recombination [21] to simultaneously delete caps and recombine the new mutation onto the existing trn28.4 null allele (see Figure 3B and Materials and Methods for details).

We mapped the nbs1-2 mutationtonthethe crystal structure of S. pombe.

Congenic Cftr MHH mice were generated by backcrossing the targeted mutation onto the B6 inbred background.

To obtain CIA-susceptible Fas mutant mice, we backcrossed the lpr mutation onto the susceptible DBA/1J background for at least six generations.

Modeling the mutation onto the Nbs1 crystal structure predicts that the bulky phenylalanine will occlude part of the phospho-threonine binding pocket and should alter Ctp1 Nbs1 interactions.

Furthermore, in silico mutational analysis was initiated by mapping the deleterious mutations onto the available 3D structure with the help of Swiss-PdbViewer [ 33].

Mapping 120 MPS IV A missense mutations onto the structure reveals that a majority of mutations affect the hydrophobic core of the structure, indicating that most MPS IV A cases result from misfolding of GALNS.

Mapping the mutations onto the atomic structure of BbCRASP-1 reveals that, in contrast to earlier assumption, the C-terminal mutations act indirectly on FHL-1 and factor H binding, whilst the region 1 mutations map the site of direct complement regulator interaction.

Mapping of disease-related mutations onto the Nav1.7 structure model is highlighted by different colors.

Mapping of human mucolipidosis type IV mutations onto the structure of an mTRPML1 subunit.