Sentence examples for mutation of such from inspiring English sources

"I don't know how well she would have been doing as a scientist in academia describing the mutation of such or such protein," says Delgado, whose lab has collaborated with Cellerix over the years.

Mutation of such factors facilitates unlimited proliferation in cancer cells [20].

11 Mutation of such residues generally renders the protein inactive.

Indeed, targeting protein sites involved in SD + SL interactions with a drug would render any mutation of such sites, lethal.

Oncogenic mutation of such clients, however, leads to higher requirements for HSP90 function, presumably because of an exaggerated conformational instability of the mutant".

Transcription factor binding events at regulatory elements are predicted by the presence of conserved binding motifs and the mutation of such motifs allows the specific activity of a class of transcription factors to be determined.

The presence of accompanying mutations of such oncogenes as RAS isoforms has also been shown to be an important determinant of the Sprouty's deregulation and mode of action.

This study provides insights into the biological function of repetitive sequences in regulating gene expression and shows how mutations of such elements can influence the progression of a human genetic disease.

Indeed, several mutations of such proteins have been found in tumors, including Cbl, TSG101 (an ESCRT-I subunit), and VPS25 (an ESCRT-II subunit) (recently reviewed in (Haglund et al. 2007)).

By "nonrandom mutation" we will mean that the mutation that drives evolution is not accidental it is not an unintended disruption of the genetic code, caused for example by external agents or by oxidative stress (although mutations of such kinds do happen and can lead to disease).

It is essential to conduct studies to learn about the mutation signature of such tumors.