Sentence examples for mutation of specific from inspiring English sources

Mutation of specific Cys residues in the putative zinc finger region abolished zinc binding and drastically reduced phosphatase activity, suggesting an allosteric role of zinc in catalysis.

Mutation of specific charged and polar residues on MHs 4 6 resulted in a decrease or loss of protein activity as measured by complementation assays in yeast.

These results support the hypothesis that mutation of specific residues in Lhp1 changes its Karyopherin preference.

The deletion or mutation of specific miRNA genes can result in defects in all RNA species produced from the genes [3], [4].

However, mutation of specific amino acids of hANT4 improved yeast mitochondrial expression and supported growth of the AAC-deficient yeast on non-fermentable carbon sources.

To determine whether the posttranslational modification of VHL affects its protein stability and nucleocytoplasmic redistribution, we further investigated the modification of VHL by mutation of specific lysine residues.

Recent studies revealed that several neurodevelopmental disorders are caused by mutations of specific tubulin isotypes, suggesting that each tubulin isotype has distinct functions.

In the absence of auxiliary subunits, mutations of specific S4 residues mimic the gating phenotypes produced by co-assembly of Kv7.1 with either KCNE1 or KCNE3.

Accordingly, mutations and expression analyses demonstrated distinct molecular signatures associated with mutations of specific functional domains.

The mutations of specific enzymes would redirect the flux to other products.

Gain- or loss-of-function mutations of specific genes can also be easily induced by cell transfection: stable cell lines can be established within a month of transfection.