Sentence examples for mutation of single from inspiring English sources

The site-specific coupling was accomplished by mutation of single amino acids on GGBP to cysteine and subsequent thiol conjugation.

Molecular evolutionary studies also revealed the existence of pseudogenes, non-coding stretches of DNA derived by the tandem duplication and subsequent inactivation by mutation of single copy genes.

It was shown that mutation of single residues can disrupt the interaction of NOD2 and RIPK2 and to abrogate NF-κB activation in response to MDP.

Increased lifespan also has been achieved in many of the same organisms through mutation of single genes, including key effectors of the interrelated Insulin/Insulin-like growth factor 1 (Igf1)/Growth hormone (Gh) signaling pathways [2], [3].

Mutation of single amino acids which are putatively relevant for myristoylation or acylation results in partial nuclear location of ZmPti1a.

These results indicate that combined mutation of single residues in each of the two motifs (Gly2/Cys3 or Cys6/Cys7) resulted in GFP fluorescence associated with cytoplasmic granules.

In the race to identify genes that typify this dawning genomics era, her lab has developed a technique that uses retroviruses to induce mutations of single genes in zebra fish.

However, mutations of single genes account for only a small number of cases.

In addition, random mutations of single bits within a chromosome are implemented based on a probability density function enable searching more of the variable space.

Every mutation recorded in T is supported by at least two samples, so that private mutations of single sequences are disregarded.

Subsequently, point mutations of single subunits were shown to be able to decrease or increase cation selectivity of nAChR channels (see, for example, reviews by Skok [2] and Keramidas et al. [3]).