Sentence examples for mutation of low from inspiring English sources

Alignment of sequence data from each group revealed the following results: there is a variation detected in MC4R-1 betheen the 2 groups at nucleotide 35 (T-G) (sense mutation) while we detected another variation at nucleotide 19 (T-C) in MC4R-2 gene (sense mutation) of low sexual desire does.

Historically, HPAI viruses in domestic poultry, and subsequently humans, likely arose by the introduction and mutation of low pathogenic (LP) AI strains from wild birds.

Authors' response: Dr. Yanai raises a good question about the tolerance to random mutation of low coding potential TE-derived coding sequences.

Although most problems with QuikChange™ can be overcome with modification or refinement, we encountered problems in mutation of low GC sequences from cloned Sulfolobus islandicus rudivirus (SIRV) CAG38830 and CAG38833 [ 20] which we were unable to solve.

It is known that the targeted mutation of hubs (central proteins) in yeast protein-protein interaction networks is more likely to be lethal than the mutation of low degree (non-central) proteins, which is referred to as the centrality-lethality rule [ 5].

2) To estimate the variation of MAF (VAF) caused by sampling error, we have employed a bioinformatic approach to call mutations of low abundance out of the background error noise of deep sequencing data.

Our studies with loss and gain of function mutations of low-density lipoprotein receptor-related protein 5 demonstrated that GDS is a powerful inhibitor of osteoblast proliferation and bone formation that does not affect bone resorption [ 13].

These mutations are of low frequency and unlikely to serve as worthy drug targets.

However, most mutations in PDGFRA are missense mutations with low mutation scores, offsetting the effect of low mutation rate to the test statistics of PDGFRA.

In agreement with their putative roles in the hydrophobic blockage, point mutations of V411T (low expression), L944N, and L944T resulted in loss of transport activity (Fig. 2D) (V411N failed to be expressed).

However, the spectrum of TP53 mutations in regions of low incidence is unknown.