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(3) Osteopontin, another known α8β1 ligand, is deposited in the developing kidney, but mutation of its gene in vivo showed that it was not necessary for renal development.
In the event that one residue of such an interacting pair mutates, the effect of the mutation can be accommodated by the 'correlated' mutation of its interacting partner.
It reproduces by combining with other code or by the mutation of its own code.
The cell has the enviable ability to evolve through mutation of its hereditary DNA code.
Even so, the place is less an escape from Los Angeles than a further mutation of its hyperactive urban genes.
The GCN4 leucine zipper is a highly stable coiled coil which can be tuned to adopt different oligomeric states via mutation of its core residues.
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The mutation rate of COII was set to the average value found in arthropods (1.15% divergence/lineage/myrs [ 37]), and the mutation rate of ITS (0.49%, 95% PD = 0.00248-0.00727, ESS = 362) was estimated relative to COII.
Protein production is fundamental to life and therefore any organisms with mutations of its 16s rRNA are unlikely to survive.
Several mutations of its gene have been reported in cases of frontotemporal lobar degeneration (FTLD) [ 63].
Intriguingly, these anti-apoptotic effects of SPINK1 were abrogated by mutations of its protease inhibition domain.
Mutations of its B1 or a4 subunit are associated with distal renal tubular acidosis and deafness.
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